Journal: Deutsches Ärzteblatt International

Article Title: The Increase in Invasive Bacterial Infections With Respiratory Transmission in Germany, 2022/2023

doi: 10.3238/arztebl.m2023.0261

Figure Lengend Snippet: Invasive isolates (blood culture, sterile aspirate) of S. pneumoniae (n = 12 478), S. pyogenes (n = 6707), H. influenzae (n = 2037), and N. meningitidis (n = 332) per quarter (sampling date), 2017–2023, Germany (ARS, as of 11 April 2023)

Article Snippet: The Institute for Medical Microbiology at the University Hospital, RWTH Aachen University (appointed as National Reference Center [NRC] for streptococci up to the end of 2022) and the NRC for meningococci and H. influenzae receive voluntarily submitted invasive isolates of H. influenzae, N. meningitidis, S. pneumoniae , and S. pyogenes from all routine laboratories in Germany.

Techniques: Sterility, Sampling

Journal: Deutsches Ärzteblatt International

Article Title: The Increase in Invasive Bacterial Infections With Respiratory Transmission in Germany, 2022/2023

doi: 10.3238/arztebl.m2023.0261

Figure Lengend Snippet: Numbers of invasive isolates (blood culture, sterile aspirate) of S. pneumoniae, S. pyogenes, H. influenzae, and N. meningitidis relative to mean seasonal peak values by quarter, 2017–2019*

Article Snippet: The Institute for Medical Microbiology at the University Hospital, RWTH Aachen University (appointed as National Reference Center [NRC] for streptococci up to the end of 2022) and the NRC for meningococci and H. influenzae receive voluntarily submitted invasive isolates of H. influenzae, N. meningitidis, S. pneumoniae , and S. pyogenes from all routine laboratories in Germany.

Techniques: Sterility

Journal: Deutsches Ärzteblatt International

Article Title: The Increase in Invasive Bacterial Infections With Respiratory Transmission in Germany, 2022/2023

doi: 10.3238/arztebl.m2023.0261

Figure Lengend Snippet: Invasive S. pyogenes isolates (blood culture and aspirate, n = 6707) by age group per 100 000 population, per quarter (sampling date), 2017–2023, Germany (ASR, as of 11 April 2023)

Article Snippet: The Institute for Medical Microbiology at the University Hospital, RWTH Aachen University (appointed as National Reference Center [NRC] for streptococci up to the end of 2022) and the NRC for meningococci and H. influenzae receive voluntarily submitted invasive isolates of H. influenzae, N. meningitidis, S. pneumoniae , and S. pyogenes from all routine laboratories in Germany.

Techniques: Sampling

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Pharmacokinetic-Pharmacodynamic Characterization of Omadacycline against Haemophilus influenzae Using a One-Compartment In Vitro Infection Model

doi: 10.1128/AAC.02265-19

Figure Lengend Snippet: Results of dose-ranging studies carried out using the one-compartment in vitro infection model for the panel of five H. influenzae isolates exposed to omadacycline total-drug ELF AUC values ranging from 2.38 to 82.7 mg · h/liter, which were representative of dosing regimens of 12.5 to 400 mg q12h.

Article Snippet: A panel of five H. influenzae isolates was utilized in the studies described herein and was obtained from the American Type Culture Collection (ATCC) and JMI Laboratories (North Liberty, IA).

Techniques: In Vitro, Infection

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Pharmacokinetic-Pharmacodynamic Characterization of Omadacycline against Haemophilus influenzae Using a One-Compartment In Vitro Infection Model

doi: 10.1128/AAC.02265-19

Figure Lengend Snippet: Relationship between the change in log 10 CFU/ml from baseline at 24 h and omadacycline total-drug ELF AUC/MIC ratio based on the pooled data for the five H. influenzae isolates evaluated in the dose-ranging studies carried out using the one-compartment in vitro infection model.

Article Snippet: A panel of five H. influenzae isolates was utilized in the studies described herein and was obtained from the American Type Culture Collection (ATCC) and JMI Laboratories (North Liberty, IA).

Techniques: In Vitro, Infection

Journal: Journal of Clinical Laboratory Analysis

Article Title: Widespread of non‐typeable Haemophilus influenzae with high genetic diversity after two decades use of Hib vaccine in China

doi: 10.1002/jcla.23145

Figure Lengend Snippet: Carriage rates of Haemophilus influenzae isolates in different age group in two sites

Article Snippet: In the present study, H influenzae isolates collected from Chinese children with respiratory infections was monitored in Beijing and discrepancies in the epidemiology between two areas located far apart in China (Beijing City and Youyang County) were identified.

Techniques:

Journal: Journal of Clinical Laboratory Analysis

Article Title: Widespread of non‐typeable Haemophilus influenzae with high genetic diversity after two decades use of Hib vaccine in China

doi: 10.1002/jcla.23145

Figure Lengend Snippet: The results of β‐lactamase activity and antibiotic susceptibility pattern of H influenzae isolates

Article Snippet: In the present study, H influenzae isolates collected from Chinese children with respiratory infections was monitored in Beijing and discrepancies in the epidemiology between two areas located far apart in China (Beijing City and Youyang County) were identified.

Techniques: Activity Assay

Journal: Journal of Clinical Laboratory Analysis

Article Title: Widespread of non‐typeable Haemophilus influenzae with high genetic diversity after two decades use of Hib vaccine in China

doi: 10.1002/jcla.23145

Figure Lengend Snippet: Population snapshot of 190 H influenzae strains revealed by eBURST analysis. The lines indicated the presence of single locus variant links in particular sequence types (STs), which were indicated by circles. The size of the circle corresponded to the number of isolates belonging to the ST. The green ST numbers indicated isolates from Youyang Hospital, the black numbers indicated isolates from Beijing Children's Hospital, and the pink numbers indicates isolates from Youyang Hospital and Beijing Children's Hospital

Article Snippet: In the present study, H influenzae isolates collected from Chinese children with respiratory infections was monitored in Beijing and discrepancies in the epidemiology between two areas located far apart in China (Beijing City and Youyang County) were identified.

Techniques: Variant Assay, Sequencing